Therapeutic plasma exchange in the treatment of myasthenia gravis

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Practice parameters and focusing research: plasma exchange for myasthenia gravis.

published by gcaudle2 on Mon, 08/19/2013 3:02pm Title Practice parameters and focusing research: plasma exchange for myasthenia gravis. Publication Type Journal Article Year of Publication 2011 Authors Kaminski, HJ, Cutter, G, Ruff, R Journal Muscle Nerve Volume 43 Issue 5 Pagination 625-6 Date Published 2011 May ISSN 1097-4598

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Treatment of myasthenia gravis.

Myasthenia gravis is a prototypic antibody-mediated neurological autoimmune disorder. Its pathogenesis is much better understood than that of multiple sclerosis or immune neuropathies. Currently two targets in the endplate membrane are considered as autoantigens, the acetylcholine receptor (in up to 90%) and the muscle-specific kinase (MuSK, in about 5%). Fortunately, substantial therapeutic pr...

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Plasma exchange and immunosuppressive drug treatment in myasthenia gravis: no evidence for synergy.

We have investigated whether plasma exchange in myasthenia gravis synergises with additional immunosuppressive drug therapy (azathioprine, cyclophosphamide or cytosine arabinoside). Serum anti-acetylcholine receptor (AChR) antibody titres were followed over 28 days after a course of PE in 20 patients, of whom 17 were taking 20-80 mg prednisone on alternate days. No significant difference was ob...

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Thymectomy in Patients with Myasthenia Gravis

A case of myasthenia gravis in a 15 years old girl is pre·sented. The disease was present for 5 years before thymectomy was performed. Indications for thymectomy, preoperative pre­paration, anesthetic and surgical management is -discussed. 

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Maintenance plasma exchange treatment for muscle specific kinase antibody positive myasthenia gravis patients.

BACKGROUND Anti-muscle specific kinase antibody positive myasthenia gravis (MuSK MG) is often characterized by a relatively severe and progressive course, refractoriness to standard myasthenia gravis (MG) medications, and an increased risk of myasthenic crisis. We report here successful management of three MuSK MG patients using maintenance therapeutic plasma exchange (TPE) treatment for up to ...

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ژورنال

عنوان ژورنال: Indian Journal of Critical Care Medicine

سال: 2015

ISSN: 0972-5229,1998-359X

DOI: 10.4103/0972-5229.148631